Geometrical Isomerism in Double bonds and Cycloalkanes (cis-trans and E-...

Video discuss about a type of configurational or cis trans isomerism which is geometric isomerism. Dr. Rojisha V C Covers the topics

Cis trans Isomerism

-  Restricted rotation caused either by a double bond or by a cyclic structure

-  Cis-trans isomerism

-  Cis-trans isomerism in cyclic system

-  E-Z system of nomenclature

-  Relative priorities of the two groups bonded to each sp2 carbon are determined using the following rules:

-  E Z system examples











GPAT Syllabus/ Organic chemistry / Stereochemistry

GPAT Syllabus/ Organic chemistry / Stereochemistry

11. Stereochemistry

Stereochemistry. Chirality & asymmetry [introduction of the same to S, P, & N]. Definition & classification [different types of isomerisms]. Enantiomers, diastereomers. Enantiomerism & diastereomerism. Meso compounds & their optical activity. Stereochemistry in acyclic compounds. Newman projection formulae & their significance. Conformational analysis of nbutane. Absolute & relative configuration. Assigning R & S configuration based on Cahn Ingold & Prelog system. Racemic mixture- its definition & resolution. Definitions of terms stereoselective, stereospecific, Enantiomeric excess & diastereomeric excess. Stereochemistry in cyclic systems. Conformations of cyclohexane. Cis-trans relationship in cyclohexane. Prediction of stability of different conformations of 1, 2- 1,3- & 1,4- disubstituted cyclohexanes. Effect of multiple substitutions on the stability of cyclohexane conformations. Chair conformations of cis-, & trans-decalins, perhydrophenanthrenes, & a tetracyclic steroidal nucleus. An introduction to atropisomerism.

 

Lecture 1: Stereochemistry : Definition & classification [different types of isomerisms].

Lecture 2: Stereochemistry: Stereochemistry in acyclic compounds.  Newman projection formulae & their significance.

Lecture 3: Stereochemistry: Chirality & asymmetry [introduction of the same to S, P, & N]. Enantiomers, diastereomers. Enantiomerism & diastereomerism. Meso compounds & their optical activity.

Lecture 4: Stereochemistry:  relative configuration & Stereochemistry in cyclic systems.

Lecture 5: Stereochemistry: Assigning R & S configuration based on Cahn Ingold & Prelog system.

Lecture 6: Stereochemistry: Conformational analysis of nbutane. Absolute

Lecture 7: Stereochemistry: Conformations of cyclohexane. Cis-trans relationship in cyclohexane. Prediction of stability of different conformations of 1, 2- 1,3- & 1,4- disubstituted cyclohexanes. Effect of multiple substitutions on the stability of cyclohexane conformations.